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Sarcoidosis of the breasts – when should it be considered? A case report

Dominika Jaguś1, Ivan Yafimtsau2, Robert K. Mlosek3, Luiza Jonczak4, Katarzyna Roszkowska-Purska5, Katarzyna Dobruch-Sobczak6

Affiliation and address for correspondence
J Ultrason 2022; 22: e136–e139
DOI: 10.15557/JoU.2022.0022
Abstract

Sarcoidosis is a systemic inflammatory disease of unknown aetiology. Given its complex clinical presentation, the disorder frequently causes diagnostic challenges. In most cases, the primary manifestation is in the lungs and mediastinum. Breast involvement as the primary manifestation of sarcoidosis is rare, accounting for less than 1% of cases. The authors present the case of a 44-year-old woman whose disease first manifested as multiple non-specific BIRADS 4 lesions in both breasts, accompanied by axillary lymphadenopathy, detected by ultrasound examination. The lesions were not visible on mammography. The course of the disease was clinically silent, with intermittent remissions, until the complete resolution of focal breast lesions on ultrasound after two years of follow-up. The paper presents an algorithm for the management of multifocal breast pathology with associated lymphadenopathy, which led to the prompt verification of sarcoidosis.

Keywords
sarcoidosis; granulomas; ultrasonography; breast diseases; granulomatous mastitis